Research strategies & Pipelines


Translational geroscience approaches to identify evolutionarily conserved aging targets and small molecule gerotherapeutics

Preclinical drug discovery in C. elegans

Our three part strategy to identify gerotherapeutics that extend healthy lifespan and delay age-related disease

Normative aging

Small molecules and natural products are tested for improved survival and health in standard lab worm models

Disease mutants

Therapeutics are screened in age-associated and rare disease mutants to identify FDA-regulated clinical applications

Drug synergy

Novel interventions are combined with known lifespan-extending compounds to create breakthrough healthy aging therapeutics

Translational drug development

From worms to mammals to clinical trials

On the path to FDA regulatory approval, therapeutics identified in worms are validated in cell culture and small mammal models with the help of our academic partners. Based on the indication and clinical endpoints pursued, clinical trials will be performed in humans or in companion animals. We are paying close attention to the Dog Aging Project TRIAD trial and will design our trials based on insights from this study.

Meet the WormBot!

Learn about the WormBot-AI, our high-throughput robotics platform combined with neural net AI to perform high-throughput health and survival analysis in worms.

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